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Consequences of rpoB mutations missed by the GenoType MTBDRplus assay in a programmatic setting in South Africa

3 Feb 2023

Abstract excerpt

Background: Rifampicin resistance missed by commercial rapid molecular assays but detected by phenotypic assays may lead to discordant susceptibility results and affect patient management.Objective: This study was conducted to evaluate the causes of rifampicin resistance missed by the GenoType MTBDRplus and its impact on the programmatic management of tuberculosis in KwaZulu-Natal, South Africa.Methods: We...

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PMID: 36873290
DOI: 10.4102/ajlm.v12i1.1975

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