Article
Neoantigens and the tumor microenvironment play important roles in the prognosis of high-grade serous ovarian cancer.
Journal of ovarian research - 29 Jan 2022
Yang Hua, Yu Mei, Zhong Sen, You Yan, Feng Fengzhi
Abstract excerpt
BACKGROUND: Despite the consistency of patient age, disease stage and treatment options, the prognosis of different high-grade serous ovarian carcinoma (HGSOC) patients is different. Here, we sought to measure predictive biomarkers for distinct responses to platinum-based chemotherapy and immunotherapy benefits. METHODS: Sixteen HGSOC patients receiving debulking surgery and adjuvant first-line combination...
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