Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Profiling Based on KRAS/BRAF Mutation, Methylation, and Microsatellite Statuses in Serrated Lesions.

Digestive diseases and sciences - 1 Oct 2018

Sugai Tamotsu, Eizuka Makoto, Fujita Yasuko, Kawasaki Keisuke, Yamamoto Eiichiro, Ishida Kazuyuki, Yamano Hiroo, Suzuki Hiromu, Matsumoto Takayuki

Abstract excerpt

AIM: The aim of your study is to characterize serrated lesions according to their molecular patterns, specifically BRAF/KRAS mutation, methylation, and microsatellite statuses. We evaluated the molecular patterns of 163 serrated lesions, including 37 microvesicular hyperplastic polyps, 73 sessile serrated adenomas/polyps (SSA/Ps), 31 traditional serrated adenomas, and 22 SSA/Ps with cytological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinogenesis

Share to Colonic Polyps

Share to Microsatellite Instability

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to Statistics as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 29974407
DOI: 10.1007/s10620-018-5167-4
PMCID: PMC6153566

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Profiling Based on KRAS/BRAF Mutation, Methylation, and Microsatellite Statuses in Serrated Lesions.PMID 29974407Read ↗

Intermediate serrated polyp as an intermediate lesion of hyperplastic polyp and sessile serrated polyp/adenoma in terms of morphological and molecular features.Semantic proximity Read ↗

The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.Semantic proximity Read ↗

Immunohistochemical Examination is Highly Sensitive and Specific for Detection of the V600E BRAF Mutation in Colorectal Serrated Lesions.Semantic proximity Read ↗

Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis.Semantic proximity Read ↗

Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp.Semantic proximity Read ↗

Molecular and histologic considerations in the assessment of serrated polyps.Semantic proximity Read ↗

Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile.Semantic proximity Read ↗

The serrated pathway to colorectal carcinoma: current concepts and challengesSemantic proximity Read ↗

Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.Semantic proximity Read ↗

Evolving pathologic concepts of serrated lesions of the colorectumSemantic proximity Read ↗

Molecular characteristics of colorectal serrated polyps and hyperplastic polyps: A STROBE compliant article.Semantic proximity Read ↗

Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.