Article
Molecular characteristics of colorectal serrated polyps and hyperplastic polyps: A STROBE compliant article.
Medicine - 1 Dec 2016
Sambuudash Otgontuya, Kim Hee Man, Jo Hannah, Kim Hyun Sik, Lee Kyong Joo, Park Hong Jun, Kim Jae Woo, Cho Mee Yon, Kim Hyun-Soo
Abstract excerpt
The serrated neoplasia pathway of colorectal carcinogenesis is characterized by BRAF mutation and aberrant DNA methylation, which have not been reported on Korean patients. The aim of this study was to investigate BRAF mutation and DNA methylation in colorectal serrated polyps and the right colon.Between 2005 and 2013, 146 colon polyps (47 tubular adenomas [TAs], 53 traditional serrated adenomas [TSAs], 17...
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