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Article

SLCO1B1 c.521T>C Genotyping in the Austrian Population Using 2 Commercial Real-Time Polymerase Chain Reaction Assays: An Implementation Study.

Pharmacology - 1 Jan 2018

Enko Dietmar, Harringer Sophia, Oberkanins Christian, Pühringer Helene, Halwachs-Baumann Gabriele, Kriegshäuser Gernot

Abstract excerpt

Statin-induced myopathy is reported to be significantly associated with the SCLO1B1 c.521T>C polymorphism. To date, SLCO1B1 c.521T>C epidemiologic data for the Austrian population is still lacking. Therefore, this study aimed at assessing the genotype and allele frequencies of the SLCO1B1 c.521T>C variant in Austria and evaluating the clinical performance of 2 commercial real-time polymerase chain reaction...

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PMID: 29969773
DOI: 10.1159/000490619

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