Article
SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group.
BMC medical genetics - 12 Oct 2011
Santos Paulo C J L, Soares Renata A G, Nascimento Raimundo M, Machado-Coelho George L L, Mill José G, Krieger José E, Pereira Alexandre C
Abstract excerpt
BACKGROUND: Recent studies reported the association between SLCO1B1 polymorphisms and the development of statin-induced myopathy. In the scenario of the Brazilian population, being one of the most heterogeneous in the world, the main aim here was to evaluate SLCO1B1 polymorphisms according to ethnic groups as an initial step for future pharmacogenetic studies. METHODS: One hundred and eighty-two Amerindians plus...
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