Article
MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2003
Brown David A, Ward Robyn L, Buckhaults Philip, Liu Tao, Romans Katharine E, Hawkins Nicholas J, Bauskin Asne R, Kinzler Kenneth W, Vogelstein Bert, Breit Samuel N
Abstract excerpt
PURPOSE: Macrophage inhibitory cytokine-1 (MIC-1) is a divergent member of the tumor growth factor beta (TGF-beta) superfamily. Several observations suggest that it plays a role in colorectal carcinoma (CRC). In particular, MIC-1 is markedly up-regulated in colorectal cancers as well as in premal...
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