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Article

RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases.

Annals of surgical oncology - 1 Mar 2015

Zimmitti Giuseppe, Shindoh Junichi, Mise Yoshihiro, Kopetz Scott, Loyer Evelyne M, Andreou Andreas, Cooper Amanda B, Kaur Harmeet, Aloia Thomas A, Maru Dipen M, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: RAS mutations have been reported to be a potential prognostic factor in patients with colorectal liver metastases (CLM). However, the impact of RAS mutations on response to chemotherapy remains unclear. The purpose of this study was to investigate the correlation between RAS mutations and response to preoperative chemotherapy and their impact on survival in patients undergoing curative resection of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25227306
DOI: 10.1245/s10434-014-4042-6
PMCID: PMC4318708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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