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Article

Long non-coding RNA polymorphisms and prediction of response to chemotherapy based on irinotecan in patients with metastatic colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2019

Lampropoulou Dimitra-Ioanna, Aravantinos Gerasimos, Katifelis Hector, Lazaris Foivos, Laschos Konstantinos, Theodosopoulos Theodosios, Papadimitriou Christos, Gazouli Maria

Abstract excerpt

BACKGROUND: Colorectal cancer is the fourth cause of cancer related death. Drug resistance and toxicity remain major clinical issues. HOTAIR and MALAT1 are long non-coding RNAS that affect cellular proliferation, apoptosis and drug resistance; their up-regulation has been linked with a poor prognosis. OBJECTIVE: Investigation of the association between rs4759314 HOTAIR and rs3200401 MALAT1 polymorphisms and...

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Share to Antineoplastic Combined Chemotherapy Protocols
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Identifiers

PMID: 31045514
DOI: 10.3233/CBM-182383
PMCID: PMC13082408

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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