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Article

Hierarchical modeling of melanocortin 1 receptor variants with skin cancer risk.

Genetic epidemiology - 1 Sept 2018

Joshi Amit D, Li Xin, Kraft Peter, Han Jiali

Abstract excerpt

The human MC1R gene is highly polymorphic among lightly pigmented populations, and several variants in the MC1R gene have been associated with increased risk of both melanoma and nonmelanoma skin cancers. The functional consequences of MC1R gene variants have been studied in vitro and in vivo in postulated causal pathways, such as G-protein-coupled signaling transduction, pigmentation, immune response,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29968341
DOI: 10.1002/gepi.22137
PMCID: PMC6484855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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