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Article

NKG2D gene variation and susceptibility to viral bronchiolitis in childhood.

Pediatric research - 1 Sept 2018

Pasanen Anu, Karjalainen Minna K, Kummola Laura, Waage Johannes, Bønnelykke Klaus, Ruotsalainen Marja, Piippo-Savolainen Eija, Goksör Emma, Nuolivirta Kirsi, Chawes Bo, Vissing Nadja, Bisgaard Hans, Jartti Tuomas, Wennergren Göran, Junttila Ilkka, Hallman Mikko, Korppi Matti, Rämet Mika

Abstract excerpt

BACKGROUND: Genetic factors associated with bronchiolitis are inadequately characterized. We therefore inspected a selected subpopulation of our previous genome-wide association study (GWAS) of bronchiolitis for overlap with known quantitative trait loci (QTLs) to identify susceptibility loci that potentially affect mRNA and protein levels. METHODS: GWAS included a Finnish-Swedish case-control population...

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PMID: 29967528
DOI: 10.1038/s41390-018-0086-9

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