Article
Genome-Wide Association Study of Polymorphisms Predisposing to Bronchiolitis.
Scientific reports - 31 Jan 2017
Pasanen Anu, Karjalainen Minna K, Bont Louis, Piippo-Savolainen Eija, Ruotsalainen Marja, Goksör Emma, Kumawat Kuldeep, Hodemaekers Hennie, Nuolivirta Kirsi, Jartti Tuomas, Wennergren Göran, Hallman Mikko, Rämet Mika, Korppi Matti
Abstract excerpt
Bronchiolitis is a major cause of hospitalization among infants. Severe bronchiolitis is associated with later asthma, suggesting a common genetic predisposition. Genetic background of bronchiolitis is not well characterized. To identify polymorphisms associated with bronchiolitis, we conducted a genome-wide association study (GWAS) in which 5,300,000 single nucleotide polymorphisms (SNPs) were tested for...
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