Article
A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid.
Neurotoxicity research - 1 Jan 2019
Zhong Xiao-Ling, Li Jie-Qiong, Sun Li, Li Ya-Qing, Wang Hui-Fu, Cao Xi-Peng, Tan Chen-Chen, Wang Ling, Tan Lan, Yu Jin-Tai
Abstract excerpt
α-Synuclein is a 140-amino acid protein produced predominantly by neurons in the brain which plays a role in the regulation of neurotransmitter release, synaptic function, and plasticity, thus making it the focus in understanding the etiology of a group of neurodegenerative diseases. We conducted genome-wide association studies (GWAS) of α-synuclein levels in cerebrospinal fluid (CSF) with 209 non-Hispanic white...
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