Article
α-syn and SNP rs356219 as a potential biomarker in blood for Parkinson's disease in Mexican Mestizos.
Neuroscience letters - 29 May 2021
Salas-Leal Alma Cristina, Salas-Pacheco Sergio M, Gavilán-Ceniceros Jesús A Pérez, Castellanos-Juárez Francisco X, Méndez-Hernández Edna M, La Llave-León Osmel, Camacho-Luis Abelardo, Quiñones-Canales Gerardo, Romero-Gutiérrez Elizabeth, Arias-Carrión Oscar, Salas-Pacheco José M, Sandoval-Carrillo Ada A
Abstract excerpt
Clinical criteria diagnose Parkinson's disease (PD), therefore, it is crucial to find biological elements that could support diagnosis or even act as prognostic tools of PD. The SNCA gene codifies a protein called α - synuclein; several studies associate genetic and biochemical factors of SNCA with PD, including transcript and plasmatic protein levels, however, contradictory evidence indicates inconclusive...
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