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Article

Molecular dissection of large cell carcinomas of the lung with null immunophenotype.

Pathology - 1 Aug 2018

Harms Alexander, Endris Volker, Winter Hauke, Kriegsmann Mark, Stenzinger Albrecht, Schirmacher Peter, Warth Arne, Kazdal Daniel

Abstract excerpt

The aim of this study was to subcategorise large cell carcinoma (LCC) with null immunophenotype according to the World Health Organization (WHO) Classification of 2015 into the existing groups of adenocarcinoma and squamous cell carcinoma by further molecular genetic analysis. Lineage-specific molecular alterations of these tumours could depict additional therapeutic approaches. We analysed a cohort of 35 LCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29958730
DOI: 10.1016/j.pathol.2018.03.005

Genes

ALK
EGFR
KRAS
ROS1
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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