Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Comprehensive genomic profiling in large cell neuroendocrine lung cancer: the times they are a-changin'.]

Recenti progressi in medicina - 1 Jan 2021

Filetti Marco, Piras Marta, Giusti Raffaele

Abstract excerpt

The discovery of gene driver mutations and the increase of next-generation sequencing techniques have radically changed the natural history of NSCLCs. Neuroendocrine lung cancers are a heterogeneous entity whose biology is little known. Sporadic actionable mutations are also reported in this subtype of neoplasms, especially in tumors derived from a transformation of adenocarcinomas. ROS-1 gene rearrangements are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Neuroendocrine
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Mutation

Share to Protein Kinase Inhibitors

Source

Identifiers

PMID: 33512365
DOI: 10.1701/3525.35130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Comprehensive genomic profiling in large cell neuroendocrine lung cancer: the times they are a-changin'.]PMID 33512365Read ↗

Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined GroupsSemantic proximity Read ↗

Molecular and Morphological Profiling of Lung Cancer: A Foundation for “Next-Generation” Pathologists and OncologistsSemantic proximity Read ↗

Molecular Pathology of Pulmonary Large Cell Neuroendocrine Carcinoma: Novel Concepts and TreatmentsSemantic proximity Read ↗

Identification of Actionable Gene Variants in Pulmonary Large-Cell Neuroendocrine Carcinoma: A Real-World Analysis of a Polish Cohort.Semantic proximity Read ↗

New molecular classification of large cell neuroendocrine carcinoma and small cell lung carcinoma with potential therapeutic impactsSemantic proximity Read ↗

Genomic architecture of lung cancers.Semantic proximity Read ↗

New Insights into the Molecular Characteristics of Pulmonary Carcinoids and Large Cell Neuroendocrine Carcinomas, and the Impact on Their Clinical ManagementSemantic proximity Read ↗

Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.Semantic proximity Read ↗

Integrated Molecular and Clinical Characterization of Pulmonary Large Cell Neuroendocrine CarcinomaSemantic proximity Read ↗

[Molecular profiling of non-small cell lung cancer].Semantic proximity Read ↗

Real-World comprehensive genomic profiling data for diagnostic clarity in pulmonary Large-Cell neuroendocrine carcinomaSemantic proximity Read ↗

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.