Article
Next-Generation Sequencing of a Cohort of Pulmonary Large Cell Carcinomas Reclassified by World Health Organization 2015 Criteria.
Archives of pathology & laboratory medicine - 1 Apr 2016
Driver Brandon R, Portier Bryce P, Mody Dina R, Deavers Michael, Bernicker Eric H, Kim Min P, Teh Bin S, Santacruz Jose F, Kopas Lisa, Munden Reginald F, Cagle Philip T
Abstract excerpt
CONTEXT: The classification of pulmonary large cell carcinoma has undergone a major revision with the recent World Health Organization (WHO) 2015 Classification. Many large cell carcinomas are now reassigned to either adenocarcinoma with solid pattern or nonkeratinizing squamous cell carcinoma based on immunopositivity for adenocarcinoma markers or squamous cell carcinoma markers, respectively. Large cell...
Topics
- Adenocarcinoma
- Aged
- Biomarkers, Tumor
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Class I Phosphatidylinositol 3-Kinases
- Cohort Studies
- Cyclin-Dependent Kinase Inhibitor p16
- Female
- High-Throughput Nucleotide Sequencing