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Article

Large cell carcinoma of the lung: clinically oriented classification integrating immunohistochemistry and molecular biology.

Virchows Archiv : an international journal of pathology - 1 Jan 2014

Rossi G, Mengoli M C, Cavazza A, Nicoli D, Barbareschi M, Cantaloni C, Papotti M, Tironi A, Graziano P, Paci M, Stefani A, Migaldi M, Sartori G, Pelosi G

Abstract excerpt

This study aimed at challenging pulmonary large cell carcinoma (LLC) as tumor entity and defining different subgroups according to immunohistochemical and molecular features. Expression of markers specific for glandular (TTF-1, napsin A, cytokeratin 7), squamous cell (p40, p63, cytokeratins 5/6, desmocollin-3), and neuroendocrine (chromogranin, synaptophysin, CD56) differentiation was studied in 121 LCC across...

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PMID: 24221342
DOI: 10.1007/s00428-013-1501-6

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KRAS
ALK
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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