Article

The Unmet Diagnostic and Treatment Needs in Large Cell Neuroendocrine Carcinoma of the Lung

2023-07-04

Abstract excerpt

Currently, large cell neuroendocrine carcinoma of the lung (LCNEC) is classified as a rare lung cancer subtype, but given the high incidence of lung cancer, the overall number of cases is considerable. The pathologic diagnosis is based on the microscopic appearance of the tumor cells, the amount of intra-tumoral necrosis, the mitotic rate, and the presence of positive neuroendocrine markers identified by immunohis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c1b4882d-f231-5254-848f-884999212993
DOI: 10.20944/preprints202307.0229.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Unmet Diagnostic and Treatment Needs in Large Cell Neuroendocrine Carcinoma of the LungDOI 10.20944/preprints202307.0229.v1Read

Molecular Pathology of Pulmonary Large Cell Neuroendocrine Carcinoma: Novel Concepts and TreatmentsSemantic proximity Read

Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes.Semantic proximity Read

New molecular classification of large cell neuroendocrine carcinoma and small cell lung carcinoma with potential therapeutic impactsSemantic proximity Read

Pulmonary large cell neuroendocrine carcinoma: its place in the spectrum of pulmonary carcinoma.Semantic proximity Read

Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined GroupsSemantic proximity Read

Integrated Molecular and Clinical Characterization of Pulmonary Large Cell Neuroendocrine CarcinomaSemantic proximity Read

p53+/-Rb1-ASCL1low Phenotype Predicts Better Prognosis After Surgical Resection in Large Cell Neuroendocrine Carcinoma: a Molecular Characteristic and Clinical-pathological Investigation of Lung Neuroendocrine TumorsSemantic proximity Read

Molecular and Morphological Profiling of Lung Cancer: A Foundation for “Next-Generation” Pathologists and OncologistsSemantic proximity Read

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.Semantic proximity Read

Esophageal neuroendocrine carcinoma: molecular insights, diagnostic advances, and emerging treatment strategies.Semantic proximity Read

p53+/-Rb1-ASCL1low phenotype predicts better prognosis after surgical resection in large cell neuroendocrine carcinoma: a molecular characteristic and clinical-pathological investigation of lung neuroendocrine tumorsSemantic proximity Read

P53 +/- Rb1 - ASCL1 low Phenotype Predicts Better Prognosis after Surgical Resection in Large Cell Neuroendocrine Carcinoma: A Molecular Characteristic and Clinical-Pathological Investigation of Lung Neuroendocrine TumorsSemantic proximity Read