Article
Incidence and clinical significance of 491 known fusion genes in a large cohort of Japanese patients with colorectal cancer.
International journal of clinical oncology - 1 Jun 2023
Nanishi Kenji, Hino Hitoshi, Hatakeyama Keiichi, Shiomi Akio, Kagawa Hiroyasu, Manabe Shoichi, Yamaoka Yusuke, Nagashima Takeshi, Ohshima Keiichi, Urakami Kenichi, Akiyama Yasuto, Yamaguchi Ken
Abstract excerpt
BACKGROUND: The clinical significance of fusion genes in colorectal cancer remains unclear. The purpose of this study was to determine the incidence of fusion genes in colorectal cancer and explore their clinical significance by screening for common fusion genes in a large Japanese cohort. METHODS: This study involved 1588 patients. The incidence of 491 fusion genes was examined using a designed fusion panel. In...
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