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Article

Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System.

G3 (Bethesda, Md.) - 31 Jul 2018

Xu Yuanyuan, Wang Yong, Song Yuning, Deng Jichao, Chen Mao, Ouyang Hongsheng, Lai Liangxue, Li Zhanjun

Abstract excerpt

Paired-homeodomain transcription factor 4 (PAX4) gene encodes a transcription factor which plays an important role in the generation, differentiation, development, and survival of insulin-producing β-cells during mammalian pancreas development. PAX4 is a key diabetes mellitus (DM) susceptibility gene, which is associated with many different types of DM, including T1DM, T2DM, maturity onset diabetes of the young 9...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29950431
DOI: 10.1534/g3.118.300448
PMCID: PMC6071587

Genes

PAX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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