Article
Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.
Communications biology - 9 Jun 2022
Shaposhnikov Mikhail V, Guvatova Zulfiya G, Zemskaya Nadezhda V, Koval Liubov A, Schegoleva Eugenia V, Gorbunova Anastasia A, Golubev Denis A, Pakshina Natalya R, Ulyasheva Natalia S, Solovev Ilya A, Bobrovskikh Margarita A, Gruntenko Nataly E, Menshanov Petr N, Krasnov George S, Kudryavseva Anna V, Moskalev Alexey A
Abstract excerpt
Aging is one of the global challenges of our time. The search for new anti-aging interventions is also an issue of great actuality. We report on the success of Drosophila melanogaster lifespan extension under the combined influence of dietary restriction, co-administration of berberine, fucoxanthin, and rapamycin, photodeprivation, and low-temperature conditions up to 185 days in w1118 strain and up to 213 days...
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