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Article

The effect of ITLN1, XCL2 and DOT1L variants on knee osteoarthritis risk in the Han population.

Archives of orthopaedic and trauma surgery - 1 Aug 2023

Wang Cheng, Zhang Ruichun

Abstract excerpt

BACKGROUND: Knee osteoarthritis (KOA) is a complex multifactorial disease, in which genetic factors account for 50% of the risk of osteoarthritis. This study investigated the association between ITLN1, XCL2 and DOT1L variants and KOA risk in the Han population. METHODS: We applied Agena MassARRAY technology platform to genotype five single-nucleotide polymorphisms (SNPs) in 710 KOA patients and 709 controls. The...

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Source

Identifiers

PMID: 36773049
DOI: 10.1007/s00402-023-04799-w

Genes

ITLN1
XCL2
DOT1L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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