Article
Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients.
PloS one - 1 Jan 2018
Hughes-Austin Jan M, Deane Kevin D, Giles Jon T, Derber Lezlie A, Zerbe Gary O, Dabelea Dana M, Sokolove Jeremy, Robinson William H, Holers V Michael, Norris Jill M
Abstract excerpt
BACKGROUND: Extra-articular manifestations of rheumatoid arthritis (RA), potentially due to systemic inflammation, include cardiovascular disease and sarcopenic obesity. Adiponectin, an adipose-derived cytokine, has been implicated in inflammatory processes in RA, but little is known regarding its association with inflammation in a pre-clinical period. Therefore, we investigated whether adiponectin was associated...
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