Article
Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case-control study.
Arthritis research & therapy - 23 Oct 2013
Arkema Elizabeth V, Goldstein Barbara L, Robinson William, Sokolove Jeremy, Wagner Catriona A, Malspeis Susan, Rosner Bernard, Grodstein Francine, Karlson Elizabeth W, Costenbader Karen H
Abstract excerpt
INTRODUCTION: The aim of this study was to characterize anti-citrullinated peptide antibody (ACPA) serostatus in pre-clinical rheumatoid arthritis (RA) with and without Human Leukocyte Antigen-Shared Epitope (HLA-SE) alleles. METHODS: We identified 192 women in the Nurses' Health Study cohorts with blood samples obtained 4 months to 17 years prior to medical record-confirmed RA diagnosis. Three controls were...
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