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Article

Rheumatoid arthritis phenotype at presentation differs depending on the number of autoantibodies present.

Annals of the rheumatic diseases - 1 Apr 2017

Derksen V F A M, Ajeganova S, Trouw L A, van der Helm-van Mil A H M, Hafström I, Huizinga T W J, Toes R E M, Svensson B, van der Woude D

Abstract excerpt

OBJECTIVES: In rheumatoid arthritis (RA), seropositive and seronegative disease may be two entities with different underlying pathophysiological mechanisms, long-term outcomes and disease presentations. However, the effect of the conjoint presence of multiple autoantibodies, as proxy for a more pronounced humoral autoimmune response, on clinical phenotype remains unclear. Therefore, this study investigates the...

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Identifiers

PMID: 28283528
DOI: 10.1136/annrheumdis-2016-209794

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