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Article

Telomere deregulations possess cytogenetic, phenotype, and prognostic specificities in acute leukemias.

Experimental hematology - 1 Feb 2011

Capraro Valérie, Zane Linda, Poncet Delphine, Perol David, Galia Perrine, Preudhomme Claude, Bonnefoy-Berard Nathalie, Gilson Eric, Thomas Xavier, El-Hamri Mohamed, Chelghoun Youcef, Michallet Mauricette, Wattel Eric, Mortreux Franck, Sibon David

Abstract excerpt

OBJECTIVE: Telomeres are protected by tightly regulated factors and elongated by telomerase. Short and/or deprotected chromosomes are recombinogenic and thereby cancer prone. MATERIALS AND METHODS: Together with the quantification of telomerase activity (TA), measuring telomere length (TL) and expression of the genes that govern telomere protection and elongation are useful for assessing telomere homeostasis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21056083
DOI: 10.1016/j.exphem.2010.10.008

Genes

RAD50

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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