Article
Polymorphism of glutathione S-transferase Omega gene: association with risk of childhood acute lymphoblastic leukemia.
Journal of cancer research and clinical oncology - 1 May 2009
Pongstaporn W, Pakakasama S, Sanguansin S, Hongeng S, Petmitr Songsak
Abstract excerpt
PURPOSE: To evaluate the association between glutathione S-transferase Omega (GSTO) genes polymorphism and the susceptibility of acute lymphoblast leukemia (ALL). METHODS: The polymorphism of GSTO1 and GSTO2 genes were analyzed in 99 ALL patients compared with 100 healthy children by PCR-based restriction fragment length polymorphism (RFLP) analysis. RESULTS: GSTO1*A140D polymorphism was significantly associated...
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