Article
Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays.
Cancer cell - 13 Feb 2017
Li Jun, Zhao Wei, Akbani Rehan, Liu Wenbin, Ju Zhenlin, Ling Shiyun, Vellano Christopher P, Roebuck Paul, Yu Qinghua, Eterovic A Karina, Byers Lauren A, Davies Michael A, Deng Wanleng, Gopal Y N Vashisht, Chen Guo, von Euw Erika M, Slamon Dennis, Conklin Dylan, Heymach John V, Gazdar Adi F, Minna John D, Myers Jeffrey N, Lu Yiling, Mills Gordon B, Liang Han
Abstract excerpt
Cancer cell lines are major model systems for mechanistic investigation and drug development. However, protein expression data linked to high-quality DNA, RNA, and drug-screening data have not been available across a large number of cancer cell lines. Using reverse-phase protein arrays, we measured expression levels of ∼230 key cancer-related proteins in >650 independent cell lines, many of which have publically...
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