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Article

IL-3 Is a Marker of Encephalitogenic T Cells, but Not Essential for CNS Autoimmunity.

Frontiers in immunology - 1 Jan 2018

Lee Priscilla W, Xin Matthew K, Pei Wei, Yang Yuhong, Lovett-Racke Amy E

Abstract excerpt

Identifying molecules that are differentially expressed in encephalitogenic T cells is critical to the development of novel and specific therapies for multiple sclerosis (MS). In this study, IL-3 was identified as a molecule highly expressed in encephalitogenic Th1 and Th17 cells, but not in myelin-specific non-encephalitogenic Th1 and Th17 cells. However, B10.PL IL-3-deficient mice remained susceptible to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29915594
DOI: 10.3389/fimmu.2018.01255
PMCID: PMC5994593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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