Article
Metabolic effects of genetic variation in the human REPIN1 gene.
International journal of obesity (2005) - 1 Apr 2019
Krüger Jacqueline, Berger Claudia, Weidle Kerstin, Schleinitz Dorit, Tönjes Anke, Stumvoll Michael, Blüher Matthias, Kovacs Peter, Klöting Nora
Abstract excerpt
BACKGROUND: Replication initiator 1 (Repin1) is a zinc finger protein highly expressed in liver and adipose tissue. The Repin1 resides within a quantitative trait locus (QTL) for body weight and triglyceride levels in the rat, and its hepatic deletion in mice results in improved insulin sensitivity and lower body weight. Here, we analyzed whether genetic variation within the Repin1 affects parameters of glucose...
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