Article
Triplet repeat in the Repin1 3'-untranslated region on rat chromosome 4 correlates with facets of the metabolic syndrome.
Diabetes/metabolism research and reviews - 1 Jul 2007
Klöting Nora, Wilke Barbara, Klöting Ingrid
Abstract excerpt
BACKGROUND: Congenic and subcongenic rat strains confirmed the quantitative trait loci (QTLs) for facets of the metabolic syndrome between 60.53 and 77.11 Mb on chromosome 4. The analysis of candidate genes in this region favoured the replication initiator 1 (Repin1) characterized by a SNP in the coding region and a triplet repeat (TTT) in the 3'-untranslated region (3'UTR). METHODS: We analysed nine rat strains...
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