Article
Regulation and Function of TMEM16F in Renal Podocytes.
International journal of molecular sciences - 18 Jun 2018
Schenk Laura K, Ousingsawat Jiraporn, Skryabin Boris V, Schreiber Rainer, Pavenstädt Hermann, Kunzelmann Karl
Abstract excerpt
The Ca2+-activated phospholipid scramblase and ion channel TMEM16F is expressed in podocytes of renal glomeruli. Podocytes are specialized cells that form interdigitating foot processes as an essential component of the glomerular filter. These cells, which participate in generation of the primary urine, are often affected during primary glomerular diseases, such as glomerulonephritis and secondary hypertensive or...
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