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Article

Methods to analyze subcellular localization and intracellular trafficking of Claudin-16.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Kausalya P Jaya, Hunziker Walter

Abstract excerpt

The integral tight junction protein Claudin-16 (Cldn16) is predominantly expressed in renal epithelial cells of the thick ascending limb of Henle's loop where, together with claudin-19, it forms a cation-selective pore that allows influx of Na+ from the interstitial fluid into the lumen of the kidney tubule. This leads to an electrochemical gradient that drives the reabsorbtion of Mg2+ and Ca2+ ions from the...

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Identifiers

PMID: 21717354
DOI: 10.1007/978-1-61779-185-7_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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