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Article

Lack of complex type N-glycans lessens aberrant neuronal properties.

PloS one - 1 Jan 2018

Hall M Kristen, Weidner Douglas A, Whitman Austin A, Schwalbe Ruth A

Abstract excerpt

Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-N-asparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of branching, fucose and sialic acid residues. Previously, we silenced Mgat2 in neuroblastoma (NB) cells, which halted the conversion of hybrid type N-glycans to complex type, to generate a novel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29902282
DOI: 10.1371/journal.pone.0199202
PMCID: PMC6002081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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