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Ganglioside Profiling Uncovers Distinct Patterns in High-Risk Neuroblastoma

29 Aug 2025

Abstract excerpt

High-risk (HR) neuroblastoma (NBL) patients often receive standardized treatment despite wide variations in clinical outcomes, underscoring the need for improved stratification tools. A distinguishing feature of NBL is the patient-specific expression of gangliosides (GGs), particularly GD2, which may serve as biomarkers. We analyzed GG profiles in 18 patient-derived tumors and 11 NBL cell lines using thin-layer...

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PMID: 40943355
DOI: 10.3390/ijms26178431

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