Article
Prognostic gene expression and microRNA profiling signatures and genetic alterations in primary testicular diffuse large B-cell lymphoma.
Blood cancer journal - 17 Jul 2025
Shi Wenyu, Xu-Monette Zijun Y, Jia Youchao, Tzankov Alexandar, Go Heounjeong, Li Ling, Ponzoni Maurilio, Wang Yafei, Zhai Qiongli, Perry Anamarija M, Wang Shi, Wang Xiaoxiao, Chiu April, Xu Mina L, Visco Carlo, Dybkaer Karen, Withers Henry, Long Mark, Yuan Alyssa F, Miao Yi, Macias Everardo, Wu Dehong, Shuai Wen, Wang Bangchen, Li Jianyong, Bhagat Govind, Zu Youli, Pan Zenggang, Choi William, Montes-Moreno Santiago, Chen Weina, Krieken J Han van, Møller Michael B, Yu Xinfang, Parsons Benjamin M, Zhang Shanxiang, Hsi Eric D, Sohani Aliyah R, Abramson Jeremy S, Ferreri Andrés J M, Xu Bing, Li Yong, Young Ken H
Abstract excerpt
Primary testicular (PT) diffuse large B-cell lymphoma (DLBCL) is a rare and aggressive lymphoma with distinct clinical and molecular characteristics. To identify prognostic biomarkers in PT-DLBCL, in this study we analyzed DNA and RNA samples of PT-DLBCL tumors from 206 patients using next-generation sequencing platforms and assays. Genetic alteration analysis found that multiple chromosomal copy number...
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