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Autophagy in cancer: a complex relationship

11 Jun 2018

Abstract excerpt

Macroautophagy is the process by which cells package and degrade cytosolic components, and recycle the breakdown products for future use. Since its initial description by Christian de Duve in the 1960s, significant progress has been made in understanding the mechanisms that underlie this vital cellular process and its specificity. Furthermore, macroautophagy is linked to pathologic conditions such as cancer and...

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PMID: 29891531
DOI: 10.1042/bcj20170847

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