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Unraveling the Intricacies of Autophagy and Mitophagy: Implications in Cancer Biology

30 Nov 2023

Abstract excerpt

Autophagy is an essential lysosome-mediated degradation pathway that maintains cellular homeostasis and viability in response to various intra- and extracellular stresses. Mitophagy is a type of autophagy that is involved in the intricate removal of dysfunctional mitochondria during conditions of metabolic stress. In this review, we describe the multifaceted roles of autophagy and mitophagy in normal physiology...

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PMID: 38067169
DOI: 10.3390/cells12232742

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