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Article

The multiple roles of autophagy in cancer

11 Feb 2011

Abstract excerpt

Autophagy is an evolutionarily conserved, catabolic process that involves the entrapment of cytoplasmic components within characteristic vesicles for their delivery to and degradation within lysosomes. Autophagy is regulated via a group of genes called AuTophaGy-related genes and is executed at basal levels in virtually all cells as a homeostatic mechanism for maintaining cellular integrity. The levels and cargos...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21317301
DOI: 10.1093/carcin/bgr031

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