Article
Autophagy and Hallmarks of Cancer
1 Jan 2018
Abstract excerpt
Autophagy is a catabolic program that is responsible for the degradation of dysfunctional or unnecessary proteins and organelles to maintain cellular homeostasis. Mechanistically, it involves the formation of double-membrane autophagosomes that sequester cytoplasmic material and deliver it to lysosomes for degradation. Eventually, the material is recycled back to the cytoplasm. Abnormalities of autophagy often...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
