Article
MEGF10, a Glioma Survival-Associated Molecular Signature, Predicts IDH Mutation Status.
Disease markers - 1 Jan 2018
Li Guanzhang, Wang Zhiliang, Zhang Chuanbao, Liu Xing, Yang Fuqiang, Sun Lihua, Liang Jingshan, Hu Huimin, Liu Yanwei, You Gan, Bao Zhaoshi, Zhang Wei, Wang Zheng, Jiang Tao
Abstract excerpt
Glioma is the most common primary brain tumor with various genetic alterations; among which, IDH mutation is the most common mutation and plays an important role in glioma early development, especially in lower grade glioma (LGG, WHO II-III). Previous studies have found that IDH mutation is tightly associated with extensive methylation across whole genome in glioma. To further investigate the role of IDH, we...
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