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Article

LRRFIP1, an epigenetically regulated gene, is a prognostic biomarker and predicts malignant phenotypes of glioma.

CNS neuroscience & therapeutics - 1 Jun 2022

Ma Wenping, Bao Zhaoshi, Qian Zenghui, Zhang Kenan, Fan Wenhua, Xu Jianbao, Ren Changyuan, Zhang Ying, Jiang Tao

Abstract excerpt

AIMS: Glioblastoma (GBM) is the most common malignant brain tumor with an adverse prognosis in the central nervous system. Traditional histopathological diagnosis accompanied by subjective deviations cannot accurately reflect tumor characteristics for clinical guidance. DNA methylation plays a critical role in GBM genesis. The focus of this project was to identify an effective methylation point for the...

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Identifiers

PMID: 35338570
DOI: 10.1111/cns.13817
PMCID: PMC9062568

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