Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas.

Cancer letters - 28 Sept 2018

Huang Guo-Hao, Du Lei, Li Ningning, Zhang Ying, Xiang Yan, Tang Jun-Hai, Xia Shuli, Zhang Eric Erquan, Lv Sheng-Qing

Abstract excerpt

Gliomas with isocitrate dehydrogenases gene mutations (IDHMT) were found to be less aggressive than their wildtype (IDHWT) counterparts. However, the mechanism remains unclear. The current study aims to investigate the role of silenced oncogenic microRNAs in IDHMT gliomas, which were largely ignored and may contribute to the less aggressive behavior of IDHMT gliomas. Microarrays, bioinformatics analysis of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to CpG Islands

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to MicroRNAs

Share to Neoplasm Invasiveness

Source

Identifiers

PMID: 29885519
DOI: 10.1016/j.canlet.2018.06.007

Genes

MMP14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas.PMID 29885519Read ↗

Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.Semantic proximity Read ↗

MiR-148a increases glioma cell migration and invasion by downregulating GADD45A in human gliomas with IDH1 R132H mutations.Semantic proximity Read ↗

Prognostic relevance of miRNA-155 methylation in anaplastic glioma.Semantic proximity Read ↗

R132H mutation in IDH1 gene reduces proliferation, cell survival and invasion of human glioma by downregulating Wnt/β-catenin signaling.Semantic proximity Read ↗

Identification of subsets of IDH-mutant glioblastomas with distinct epigenetic and copy number alterations and stratified clinical risksSemantic proximity Read ↗

Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancersSemantic proximity Read ↗

Integrated analysis of the genomic and transcriptional profile of gliomas with isocitrate dehydrogenase-1 and tumor protein 53 mutations.Semantic proximity Read ↗

Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical ImplicationsSemantic proximity Read ↗

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.Semantic proximity Read ↗

Identification Of Immune Networks Influenced By Mir-200c In IDH1-Mutant Lower-Grade Gliomas Using WGCNASemantic proximity Read ↗

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human gliomaSemantic proximity Read ↗

m1A RNA Methylation Regulators Contribute To Malignant Progression And Have Clinical Prognostic Impact In GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.