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Article

Data integration for functional annotation of regulatory single nucleotide polymorphisms associated with Alzheimer's disease susceptibility.

Gene - 25 Sept 2018

Amber Sanila, Zahid Saadia

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD), the most common form of dementia affects 24.3 million people worldwide. More than twenty genetic loci have been associated with AD and a significant number of genetic variants were mapped within these loci. A large proportion of genome wide significant variants lie outside the coding region. However, the plausible function of these variants is still unexplored. OBJECTIVE: The...

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PMID: 29883757
DOI: 10.1016/j.gene.2018.06.011

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