Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease.

Molecular neurobiology - 1 Jan 2016

Bai Zhouxian, Han Guangchun, Xie Bin, Wang Jiajia, Song Fuhai, Peng Xing, Lei Hongxing

Abstract excerpt

Alzheimer's disease (AD) affects a significant portion of elderly people worldwide. Although the amyloid-β (Aβ) cascade hypothesis has been the prevailing theory for the molecular mechanism of AD in the past few decades, treatment strategies targeting the Aβ cascade have not demonstrated effectiveness as yet. Thus, elucidating the spatial and temporal evolution of the molecular pathways in AD remains to be a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Alzheimer Disease
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Gene Expression Profiling

Share to Gene Expression Regulation

Share to Gene Regulatory Networks

Share to Genetic Predisposition to Disease

Source

Identifiers

PMID: 25432889
DOI: 10.1007/s12035-014-9011-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease.PMID 25432889Read ↗

Dysregulated gene-associated biomarkers for Alzheimer’s disease and agingSemantic proximity Read ↗

Alzheimer's Disease: Genomics and Beyond.Semantic proximity Read ↗

Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analysesSemantic proximity Read ↗

An integrated brain-specific network identifies genes associated with neuropathologic and clinical traits of Alzheimer's disease.Semantic proximity Read ↗

Alzheimer’s Disease: From Genetic Variants to the Distinct Pathological MechanismsSemantic proximity Read ↗

Identification of dysregulated genes and pathways of different brain regions in Alzheimer’s diseaseSemantic proximity Read ↗

Genome-wide prediction and integrative functional characterization of Alzheimer’s disease-associated genesSemantic proximity Read ↗

Exploring Potential Biomarkers Underlying the Pathogenesis of Alzheimer's Disease by Bioinformatics Gene Analysis.Semantic proximity Read ↗

Biological and disease hallmarks of Alzheimer’s disease defined by Alzheimer’s disease genesSemantic proximity Read ↗

Exploring the Key Genes and Identification of Potential Diagnosis Biomarkers in Alzheimer’s Disease Using Bioinformatics AnalysisSemantic proximity Read ↗

Genomic variants, genes, and pathways of Alzheimer's disease: An overview.Semantic proximity Read ↗

Dissecting Complex and Multifactorial Nature of Alzheimer's Disease Pathogenesis: a Clinical, Genomic, and Systems Biology Perspective.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.