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Article

Connecting the dots: potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS findings.

PloS one - 1 Jan 2014

Rosenthal Samantha L, Barmada M Michael, Wang Xingbin, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

Late-onset Alzheimer's disease (LOAD) is a multifactorial disorder with over twenty loci associated with disease risk. Given the number of genome-wide significant variants that fall outside of coding regions, it is possible that some of these variants alter some function of gene expression rather than tagging coding variants that alter protein structure and/or function. RegulomeDB is a database that annotates...

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PMID: 24743338
DOI: 10.1371/journal.pone.0095152
PMCID: PMC3990600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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