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High‐throughput and multi‐phases identification of autoantibodies in diagnosing early‐stage breast cancer and subtypes

29 Nov 2021

Abstract excerpt

Autoantibodies (AAbs) targeted tumor-associated antigens (TAAs) have the potential for early detection of breast cancer. Here, 574 early-stage breast cancer (ES-BC) patients containing 4 subtypes (Luminal A, Luminal B, HER2+, TN), 126 benign breast disease (BBD) patients, and 199 normal healthy controls (NHC) were separated into three-phases to discover, verify, and validate AAbs. In discovery phase using...

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PMID: 34843149
DOI: 10.1111/cas.15227

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