Article
Genome-Wide Association Studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Dehghan Abbas
Abstract excerpt
Genetic association studies have made a major contribution to our understanding of the genetics of complex disorders over the last 10 years through genome-wide association studies (GWAS). In this chapter, we review the key concepts that underlie the GWAS approach. We will describe the "common disease, common variant" theory, and will review how we finally afforded to capture the common variance in genome to make...
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