Article
Genome-wide association studies: results from the first few years and potential implications for clinical medicine.
Annual review of medicine - 1 Jan 2011
Hirschhorn Joel N, Gajdos Zofia K Z
Abstract excerpt
Most common diseases and quantitative traits are heritable: determined in part by genetic variation within the population. The inheritance is typically polygenic in that combined effects of variants in numerous genes, plus nongenetic factors, determine outcome. The genes influencing common disease and quantitative traits remained largely unknown until the implementation in 2006 of genome-wide association (GWA)...
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